Economic & Healthcare Rationale

Delayed bacterial confirmation impacts patients, hospitals, and healthcare costs.

12-72 HRS
CULTURE TURNAROUNDPMID 30135230
01

Patient Impact

+9%

PER HOUR

Higher adjusted odds of hospital mortality per hour of antibiotic delay in sepsis.

LIU ET AL. / 2017PMID 28345952
1 in 3

SEPTIC SHOCK MORTALITY

U.S. sepsis encounters involving septic shock resulting in death, 2021.

AHRQ / 2024AHRQ 2024
1.27M

AMR DEATHS

Global deaths directly attributable to bacterial antimicrobial resistance in 2019.

LANCET / 2022PMID 35065702
02

Hospital Impact

8 DAYS

SHORTER STAY

23.3 versus 15.3 hospital days after rapid diagnostics plus stewardship in resistant Gram-negative bacteremia.

PEREZ ET AL. / 2014PMID 24841135
16.7M

HOSPITAL DAYS

Annual U.S. inpatient days associated with sepsis, 2021.

AHRQ / 2024AHRQ 2024
2.5M

INPATIENT STAYS

U.S. sepsis-related hospitalizations, 2021.

AHRQ / 2024AHRQ 2024
03

Economic Impact

PER DAY / PER CASE

$550

PER HOSPITAL DAY

Institution-specific inpatient-day cost assumption used in a rapid-testing economic model.

ROTH ET AL. / 2022PMID 35203725
$2,439

LOWER COST PER CASE

Observed cost difference per bloodstream infection after rapid testing plus stewardship.

PATEL ET AL. / 2017PMID 27795335
$26,298

LOWER COST PER SURVIVOR

Reduced hospital cost per inpatient survivor in resistant Gram-negative bacteremia.

PEREZ ET AL. / 2014PMID 24841135

ANNUAL / NATIONAL

$2.34M

ESTIMATED ANNUAL SAVINGS

Hospital-level estimate following rapid testing and stewardship.

PATEL ET AL. / 2017PMID 27795335
$2.4M

ESTIMATED ANNUAL SAVINGS

Hospital-level estimate in resistant Gram-negative bacteremia.

PEREZ ET AL. / 2014PMID 24841135
$52.1B

U.S. HOSPITAL COSTS

Aggregate national sepsis-related hospitalization costs in 2021.

AHRQ / 2024AHRQ 2024